产品货号:
Z32577
中文名称:
Aquaporin 4/AQP4抗体
英文名称:
Anti-Aquaporin 4/AQP4 Antibody (Clone#4H1)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Aquaporin 4/AQP4 Antibody (Clone#4H1) |
指标别名 | AQP 4;AQP4;aquaporin 4;NMO-IgG |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | IF,IHC,ICC,WB |
基因名称 | AQP4 |
克隆号 | 4H1 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Synthetic peptide of Aquaporin 4 |
计算分子量 | 35KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Aquaporin 4 is found in the basolateral cell membrane of principal collecting duct cells and provides a pathway for water to exit these cells.The gene of AQP4 is mapped to 18q11.2-q12.1.Similar to other aquaporins,the AQP4 gene is composed of 4 exons encoding 127,55,27,and 92 amino acids separated by introns of 0.8,0.3,and 5.2kb.Unlike other aquaporins,an alternative coding initiation sequence (designated exon 0) was located 2.7kb upstream of exon 1.When spliced together,M1 and the subsequent 10 amino acids are encoded by exon 0;the next 11 amino acids and M23 are encoded by exon 1.AQP4 is expressed in astrocytes and is upregulated by direct insult to the central nervous system.And AQP4 is the predominant water channel in the brain and has an important role in brain water homeostasis.It is abundant in mammalian brain and is concentrated in astrocytic foot processes at the blood-brain barrier. |
Uniprot ID | P55087 |
基因名全称 | Aquaporin-4 |
蛋白名全称 | Aquaporin-4 |
推荐稀释比 | WB 1:1000 IF 1:100~200 IHC 1:50~300 |
相关搜索:Aquaporin 4/AQP4抗体,Aquaporin 4抗体,AQP4单抗,Anti-Aquaporin 4/AQP4 Antibody (Clone#4H1)